RESUMO
Warnerin pretreatment of catheter segments subcutaneously implanted to mice under conditions of immunosuppression led to a significant increase in the number of neutrophils in the surrounding tissues on day 1; the number of fibroblasts tended to decrease by day 3. Immunohistochemical study showed the presence of T and B lymphocytes on day 3, but no positive reactions to vimentin and CD34 were observed during the first 2 days. These changes suggest that warnerin reduced the intensity of regeneration processes in tissues around the implant, which can be used for suppression of fibrosis.
Assuntos
Peptídeos Catiônicos Antimicrobianos/farmacologia , Bacteriocinas/farmacologia , Ciclofosfamida/administração & dosagem , Imunossupressores/administração & dosagem , Politetrafluoretileno/farmacologia , Regeneração/efeitos dos fármacos , Animais , Animais não Endogâmicos , Antígenos CD/genética , Antígenos CD/imunologia , Linfócitos B/efeitos dos fármacos , Linfócitos B/imunologia , Biomarcadores/metabolismo , Cateteres de Demora , Fibrose/prevenção & controle , Expressão Gênica , Macrófagos/efeitos dos fármacos , Macrófagos/imunologia , Mastócitos/efeitos dos fármacos , Mastócitos/imunologia , Camundongos , Neutrófilos/efeitos dos fármacos , Neutrófilos/imunologia , Regeneração/imunologia , Tela Subcutânea/imunologia , Linfócitos T/efeitos dos fármacos , Linfócitos T/imunologia , Vimentina/genética , Vimentina/imunologiaRESUMO
The authors compare the effects of central electroanalgesia and premedication in hypertensive stomatological patients, administered to prepare the patients to treatment. In contrast to premedication, central electroanalgesia normalized (stabilized) the arterial pressure and pulse rate and did not reduce the rate of reaction to a light stimulus.
Assuntos
Anestesia Dentária/métodos , Assistência Odontológica/métodos , Hipertensão/psicologia , Estimulação Elétrica Nervosa Transcutânea/métodos , Adulto , Idoso , Doença Crônica , Ansiedade ao Tratamento Odontológico/fisiopatologia , Ansiedade ao Tratamento Odontológico/prevenção & controle , Ansiedade ao Tratamento Odontológico/psicologia , Assistência Odontológica/psicologia , Clínicas Odontológicas , Feminino , Humanos , Hipertensão/fisiopatologia , Masculino , Pessoa de Meia-Idade , Medicação Pré-AnestésicaRESUMO
The growth kinetics of plasmid and nonplasmid strains of 2 isogenic E. coli K12 culture lines has been studied in experiments on batch and continuous cultivation. Under the optimum conditions the growth rate of R+- and R- cells is the same; under the conditions of limited glucose supply the plasmid strains grown slower, as their energy is partly spent on maintaining plasmids in the cell.
Assuntos
Escherichia coli/genética , Plasmídeos , Aerobiose , Anaerobiose , Conjugação Genética , Meios de Cultura/metabolismo , Escherichia coli/crescimento & desenvolvimento , Cinética , Fatores RRESUMO
The aim of this work was to investigate phenol decomposition by Candida tropicalis 29-10 adapted to phenol as a sole source of carbon and energy, and to elucidate the nature of resistance of continuous cultures decomposing phenol in processes with two types of control, viz. in chemostat and in pH-stat. The results suggest the resistance of the pH-stat regime of microbial cultivation during substrate inhibition. A region of instability in the chemostat cultivation has been determined when the yeast growth was inhibited with phenol.